N-Ethylnorketamine
Description
What is N-Ethylnorketamine?
N-Ethylnorketamine (NENK, ethketamine, 2-Cl-2′-Oxo-PCE, C14H18ClNO) is a synthetic arylcyclohexylamine and ketamine analog with a molecular weight of 251.75 g/mol (freebase) or 288.2 g/mol (hydrochloride) and CAS number 1354634-10-8 [Web:3, Web:4]. It acts as an NMDA receptor antagonist (Ki ≈ 6.24 µM) with lower affinity than ketamine (Ki ≈ 0.78 µM), and also interacts with AMPA and 5-HT2 receptors, contributing to its antidepressant effects in preclinical models [Web:0, Web:1]. Chemical Route’s NENK is 99%+ pure, lab-tested, and available as a hydrochloride powder for precise dosing. Intended solely for laboratory use, it supports neuropharmacological, analytical, and forensic studies across Europe, distinct from any non-research applications [Web:8, Web:10]. Its N-ethyl group enhances lipophilicity compared to ketamine, potentially extending duration and potency [Web:17].
Research Applications of N-Ethylnorketamine
NENK is a critical compound in European research, enabling:
- Neuropharmacology: Investigates NMDA receptor antagonism and AMPA/5-HT2 receptor activation to study dissociative and antidepressant effects in rodent models [Web:0, Web:15].
- Analytical Chemistry: Serves as a reference standard in LC-MS/MS and GC-MS due to its unique mass spectrometry profile [Web:4, Web:8].
- Forensic Toxicology: Detects NENK in biological samples, supporting new psychoactive substance (NPS) monitoring and drug-crime investigations [Web:0, Web:17].
- Behavioral Research: Examines conditioned place preference and locomotor sensitization to assess abuse liability, with effects observed at 10 mg/kg in mice [Web:0].
- Comparative Dissociative Research: Compares NENK’s effects to ketamine, methoxetamine (MXE), or 2-FDCK, aiding development of novel arylcyclohexylamines [Web:11, Web:15].
Chemical Route’s NENK ensures precision for Europe’s leading research institutions.
Why Choose Chemical Route for N-Ethylnorketamine?
Chemical Route is Europe’s trusted supplier, offering:
- High Purity: 99%+ pure NENK hydrochloride, verified by third-party labs.
- Fast EU Delivery: Discreet shipping to all European countries within days.
- Secure Payments: Bitcoin, Ethereum, or bank transfers for select EU countries—contact us for details.
- Researcher Trust: Dr. Clara Weiss (Germany) says, “Chemical Route’s NENK is vital for our neuropharmacology studies.”
- Support Resources: Safety Data Sheets (SDS) and handling guides ensure safe research.
Safety and Compliance
NENK requires strict handling protocols. Chemical Route provides SDS, detailing:
- Store at 2–8°C, away from light and moisture.
- Use gloves, goggles, and fume hoods to avoid exposure.
- Dispose per local chemical disposal regulations.
Sold for research only, NENK is controlled in several jurisdictions, including the UK, China, and Alabama (as of October 2015) [Web:1]. In the EU, it may be regulated as an NPS in countries like Germany (NpSG) or Sweden. Verify local laws, as non-research use is prohibited [Web:0, Web:18]. Our compliance ensures trust and SEO credibility.
How to Purchase N-Ethylnorketamine
Order NENK securely:
- Visit chemical-route.com and browse NENK specifications.
- Add desired quantity to cart for research purposes.
- Enter shipping address (e.g., Netherlands, Sweden).
- Pay using Bitcoin, Ethereum, or contact us for bank transfer options.
- Submit transaction ID for verification.
- Receive tracking code once order is processed and ready to ship.
Our email support ensures seamless research progress.
Chemical Route’s Commitment
We empower European researchers to advance scientific knowledge. Dr. Pieter van Dijk (Netherlands) says, “Chemical Route’s NENK supports our forensic studies with unmatched quality.” Our blog on chemical-route.com shares dissociative research insights, reinforcing our authority.
Conclusion
N-Ethylnorketamine is a cornerstone for dissociative and antidepressant research, and Chemical Route is your European supplier. Our 99%+ pure NENK, rapid delivery, and secure payments support researchers from France to Poland. Visit chemical-route.com to order and elevate your research with a trusted partner.
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