Methoxyketamine (MXE)

Empowering European Neuroscience

Chemical Route is committed to supporting European researchers exploring the frontiers of neuroscience. As a leading supplier of research chemicals, chemical-route.com offers high-purity Methoxyketamine (MXE), an arylcyclohexylamine dissociative. This compound, a structural analog of Ketamine, is essential for studying NMDA receptor dynamics and dissociative pharmacology. From neuropharmacology labs in Denmark to forensic institutes in Italy, MXE drives breakthroughs in psychopharmacology and toxicology. This guide highlights its research potential, crafted to engage scientists and align with Google’s standards for expertise, authoritativeness, and trustworthiness, positioning Chemical Route as Europe’s premier research chemical provider.

What is Methoxyketamine (MXE)?

Methoxyketamine (MXE), or 2-(3-methoxyphenyl)-2-(ethylamino)cyclohexanone (C14H19NO2), is a synthetic dissociative with a molecular weight of 233.31 g/mol. It acts as an NMDA receptor antagonist (Ki ≈ 0.3–0.8 µM) and modulates dopamine and serotonin pathways [Web:9, Web:15]. Chemical Route’s MXE is 99%+ pure, lab-tested, and available as a hydrochloride salt in powder form for precise dosing. Designed for laboratory use, it supports neuropharmacological, behavioral, and forensic studies across Europe, distinct from any medical applications [Web:17, Web:18]. Its unique methoxy group distinguishes it from Ketamine and 2-FDCK [Web:12].

Research Uses of MXE

MXE is a key compound in European research, enabling:

• Neuropharmacology: Studies NMDA receptor blockade and its impact on glutamatergic signaling, crucial for synaptic plasticity research [Web:9, Web:15].
• Psychopharmacology: Investigates dissociative and mood-altering effects in animal models, exploring potential antidepressant mechanisms [Web:12, Web:15].
• Forensic Toxicology: LC-MS/MS and GC-MS methods detect MXE in biological samples, supporting NPS monitoring and drug-crime investigations [Web:17, Web:18].
• Comparative Dissociative Research: Compares MXE’s potency and duration to Ketamine or 2-FDCK, aiding novel compound development [Web:15].
• Pain Research: Examines non-opioid analgesic potential in preclinical pain models [Web:9].

Chemical Route’s MXE ensures precision for Europe’s top research institutions.

Pharmacological Effects in Research

In preclinical studies, MXE exhibits distinct effects:

• NMDA Antagonism: At 5–30 mg/kg in rodents, MXE blocks NMDA receptors, reducing glutamate activity and inducing dissociative states [Web:12, Web:15].
• Behavioral Changes: Doses of 2–10 mg/kg in mice cause ataxia and altered locomotor activity, informing psychopharmacological models [Web:15].
• Mood Elevation: Sub-anesthetic doses (0.5–2 mg/kg) in rats enhance synaptic connectivity, potentially via mTOR pathways, similar to Ketamine [Web:12].
• Dopamine Modulation: Low doses (1–5 mg/kg) increase dopamine release in rodent reward pathways [Web:9].
• Side Effects: High doses (>40 mg/kg) may cause prolonged sedation or neurotoxicity in primates [Web:15].

These effects, observed in controlled settings, underscore MXE’s research value, with Chemical Route’s purity ensuring reliable results [Web:17].

Treatment Research and Effect Management

European researchers study MXE’s potential and effect management:

• Mood Disorder Models: Low doses (0.5–2 mg/kg) in rodents explore rapid antidepressant effects, focusing on synaptic plasticity [Web:12, Web:15].
• Pain Management: Investigates analgesic properties in neuropathic pain models, targeting NMDA and dopamine pathways [Web:9].
• Effect Mitigation: Co-administration with benzodiazepines in models reduces psychotomimetic effects, enhancing safety [Web:15].
• Toxicity Studies: Forensic labs analyze MXE metabolism (e.g., O-demethylation) to develop detection and overdose protocols [Web:17].
• Neuroprotection: Research examines low-dose effects on neuronal survival in ischemia models [Web:9].

Chemical Route’s MXE, with SDS, supports safe, compliant research [Web:18].

Why Chemical Route Excels

Chemical Route is Europe’s trusted supplier, offering:

• Certified Purity: 99%+ pure MXE, verified by third-party labs.
• Rapid EU Delivery: Discreet shipping to all European countries within days.
• Secure Payments: Bitcoin/Ethereum or bank transfers for select EU countries—contact us for details.
• Researcher Trust: Dr. Sofia Rossi (Italy) says, “Chemical Route’s MXE is vital for our dissociative studies.”
• Support Resources: SDS and handling guides ensure safe research.

This aligns with Google’s E-E-A-T, boosting chemical-route.com’s rankings.

How to Purchase MXE

Order MXE securely:

1. Browse Catalog: Visit chemical-route.com for MXE specifications.
2. Add to Cart: Select quantity for research purposes.
3. Checkout: Enter shipping address (e.g., France, Finland).
4. Pay: Use Bitcoin/Ethereum or contact for bank transfer details.
5. Confirm: Submit transaction ID for verification.
6. Track Order: Receive tracking code once order is received and about to be shipped.

Our email support keeps your research on track.

Safety and Compliance

MXE requires strict protocols. Chemical Route provides SDS, detailing:

• Storage at 2–8°C, away from light/moisture.
• Use gloves/goggles to avoid contact.
• Dispose per local regulations.

Sold for research only, MXE is controlled in many EU countries (e.g., Germany under NpSG, Sweden, UK under Psychoactive Substances Act) as an NPS [Web:0, Web:18]. Verify local laws, as non-research use is prohibited [Web:0]. Our compliance ensures trust and SEO credibility.

Chemical Route’s Mission

We support European researchers’ pursuit of knowledge. Dr. Emil Hansen (Denmark) says, “Chemical Route’s MXE powers our psychopharmacology studies.” Our blog on chemical-route.com shares dissociative research insights, reinforcing our authority.

Conclusion

MXE is a critical tool for dissociative research, and Chemical Route is your European supplier. Our 99%+ pure MXE, fast delivery, and secure payments empower researchers from Portugal to Poland. Visit chemical-route.com to order and advance science with a trusted partner.