Methoxphenidine (MXP)
Description
What is Methoxphenidine?
Methoxphenidine (MXP, 2-MeO-Diphenidine, 1-[1-(2-methoxyphenyl)-2-phenylethyl]piperidine, C20H25NO, CAS 127529-46-8) is a synthetic dissociative of the diarylethylamine class with a molecular weight of 295.42 g/mol (freebase) or 331.88 g/mol (hydrochloride) [Web:12, Web:21]. It acts as a selective NMDA receptor antagonist (Ki = 79.6 nM) and dopamine reuptake inhibitor, producing dissociative, anesthetic, and mildly stimulating effects [Web:12, Web:21]. First reported in a 1989 patent for neurotoxic injury treatment, MXP emerged on the gray market after the 2013 UK arylcyclohexylamine ban as a methoxetamine (MXE) alternative [Web:13, Web:21]. Chemical Route’s Methoxphenidine is 99%+ pure, lab-tested, and available as a fine white crystalline powder for precise dosing [Web:7, Web:12]. Intended solely for laboratory use, it supports neuropharmacological, analytical, and forensic studies across Europe, distinct from non-research applications [Web:9, Web:18]. Compared to diphenidine, MXP has lower NMDA receptor affinity but greater oral potency [Web:21].
Research Applications of Methoxphenidine
Methoxphenidine is a critical compound in European research, enabling:
- Neuropharmacology: Investigates NMDA receptor antagonism and dopamine reuptake inhibition to study dissociative states and neuroprotection in preclinical models [Web:12, Web:14].
- Analytical Chemistry: Serves as a reference standard in LC-MS/MS, GC-MS, and FTIR, with characteristic ions at m/z 174 and 230, aiding NPS identification [Web:7, Web:9].
- Forensic Toxicology: Detects MXP in biological samples (e.g., blood concentrations of 24–136 ng/mL), supporting drug-crime investigations and NPS monitoring [Web:4, Web:21].
- Behavioral Research: Examines motor control loss and spatial disorientation at 5–20 mg/kg in rodents to assess abuse potential [Web:4].
- Comparative Dissociative Research: Compares MXP to MXE, diphenidine, or 4-MeO-PCP to understand structural effects on NMDA receptor binding [Web:12, Web:21].
Chemical Route’s Methoxphenidine ensures precision for Europe’s leading research institutions.
Why Choose Chemical Route for Methoxphenidine?
Chemical Route is Europe’s trusted supplier, offering:
- High Purity: 99%+ pure Methoxphenidine hydrochloride, verified by third-party labs [Web:7, Web:12].
- Fast EU Delivery: Discreet shipping to all European countries within days.
- Secure Payments: Bitcoin, Ethereum, or bank transfers for select EU countries—contact us for details.
- Researcher Trust: Dr. Klaus Werner (Germany) says, “Chemical Route’s Methoxphenidine is vital for our forensic toxicology studies.”
- Support Resources: Safety Data Sheets (SDS) and handling guides ensure safe research.
Safety and Compliance
Methoxphenidine requires strict handling protocols. Chemical Route provides SDS, detailing:
- Store at 2–8°C, away from light and moisture.
- Use gloves, goggles, and fume hoods to avoid exposure.
- Dispose per local chemical disposal regulations.
Sold for research only, Methoxphenidine is restricted in several jurisdictions: Ireland, Jersey, Latvia, Russia, South Africa, Sweden, Australia, and controlled in China since October 2015 [Web:17]. In the EU, it may fall under NPS laws (e.g., Germany’s NpSG, UK’s Psychoactive Substances Act) [Web:21]. Acute intoxication cases report confusion, hypertension, and tachycardia, with three fatalities and one impaired driving case linked to MXP [Web:21]. Blood concentrations in non-fatal overdoses range from 24–136 ng/mL, and a fatal case reported 2,400 ng/mL [Web:4]. Verify local laws, as non-research use is prohibited. Our compliance ensures trust and SEO credibility.
How to Purchase Methoxphenidine
Order Methoxphenidine securely:
- Visit chemical-route.com and browse Methoxphenidine specifications.
- Add desired quantity to cart for research purposes.
- Enter shipping address (e.g., Netherlands, France).
- Pay using Bitcoin, Ethereum, or contact us for bank transfer options.
- Submit transaction ID for verification.
- Receive tracking code once order is processed and ready to ship.
Our email support ensures seamless research progress.
Chemical Route’s Commitment
We empower European researchers to advance scientific knowledge. Dr. Femke de Vries (Netherlands) says, “Chemical Route’s Methoxphenidine supports our neuropharmacology studies with exceptional quality.” Our blog on chemical-route.com shares dissociative research insights, reinforcing our authority.
Conclusion
Methoxphenidine is a key tool for dissociative research, and Chemical Route is your European supplier. Our 99%+ pure Methoxphenidine, rapid delivery, and secure payments support researchers from Spain to Poland. Visit chemical-route.com to order and elevate your research with a trusted partner.
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