α-Pyrrolidinoisohexanophenone HCI, a-PiHP

Product information

IUPAC-name      4-methyl-1-phenyl-2-(pyrrolidin-1-yl)pentan-1-one, monohydrochloride

Synonyms        α-PiHP, α-PHiP, α-Pyrrolidinoisohexanophenone, Alpha-PIHP, a-PiHP

Formal name      4-methyl-1-phenyl-2-(pyrrolidin-1-yl)pentan-1-one, monohydrochloride

Cas number     2181620-71-1

Formula             C₁₆H₂₃NO • HCl

Formula Weight       281.8

Formulation      A neat solid

α-Pyrrolidinoisohexanophenone also referred or known as α-PHIP, α-PIHP, is a cathinone stimulant with a structural isomer of pyrovalerone. It is a pseudo-cyclic isomer of pyrovalerone that has been sold as a designer drug. It is a relative isomer of pyrovalerone that has the 4-position of the aromatic chain. In 2006, a study revealed that the alpha-isobutyl derivatives of pyrovalerone exhibited the highest potency in vitro.

a-PiHP is structurally similar to MDPV. In rats, a-PiHP exhibits a strong stimulation effect and also considered to be a adrenaline and dopamine reuptake inhibitor.

The methyl group of the compound is shifted to the 4-position of the acyl chain from the 4-position of the aromatic ring. The alpha-isobutyl derivative of the pyrovalerone, was discovered to have the highest potency as an inhibitor of the dopamine transporter.

Not much is known about the pharmacological and toxicological properties of α-PIHP. Usage of this Chemical should be for research and forensic purposes only.

WARNING This product is not for human or veterinary use.

This product is only available to persons of 21 years old and above.

Hazard statement(s)