2-CMC

Empowering European Neuroscience

Chemical Route is dedicated to advancing European neuroscience by supplying high-purity research chemicals like 2-CMC (2-Chloromethcathinone). This synthetic cathinone, structurally similar to 3-CMC and mephedrone, is a vital tool for studying monoamine neurotransmitter systems. From psychopharmacology labs in Sweden to forensic centers in the Netherlands, 2-CMC drives discoveries in stimulant pharmacology and toxicology. This guide explores its research potential, crafted to engage scientists and align with Google’s standards for expertise, authoritativeness, and trustworthiness, positioning chemical-route.com as Europe’s trusted source for research chemicals.

What is 2-CMC?

2-CMC, or 1-(2-chlorophenyl)-2-(methylamino)-1-propanone (C10H12ClNO), is a synthetic cathinone with a molecular weight of 197.66 g/mol. It acts as a monoamine reuptake inhibitor and releasing agent, primarily targeting dopamine and norepinephrine transporters (Ki ≈ 0.5–2 µM) [Web:11, Web:14]. Chemical Route’s 2-CMC is 99%+ pure, lab-tested, and available as a hydrochloride salt in crystalline or powder form for precise dosing. Designed for laboratory use, it supports analytical chemistry, pharmacology, and forensic studies across Europe, distinct from any non-research applications [Web:14, Web:17]. Its chlorinated structure enhances its research utility compared to 3-CMC [Web:23].

Research Uses of 2-CMC

2-CMC is widely used in European research, enabling:

• Psychopharmacology: Investigates monoamine transporter interactions to study stimulant-induced behavioral changes in rodent models [Web:11, Web:14].
• Analytical Chemistry: Serves as a reference standard in mass spectrometry (MS) and high-performance liquid chromatography (HPLC) due to its distinct ionization profile [Web:14].
• Forensic Toxicology: LC-MS/MS and GC-MS methods detect 2-CMC in biological samples, aiding NPS monitoring and drug-crime investigations [Web:17, Web:18].
• Comparative Stimulant Research: Compares 2-CMC’s effects to 3-CMC or mephedrone, supporting development of novel cathinones [Web:11, Web:23].
• Neurochemistry: Examines dopamine release and locomotor activity in preclinical models to explore reward pathways [Web:14].

Chemical Route’s 2-CMC ensures precision for Europe’s leading research institutions [Web:14].

Pharmacological Effects in Research

In preclinical studies, 2-CMC exhibits distinct effects:

• Monoamine Release: At 1–10 mg/kg in rats, 2-CMC enhances dopamine and norepinephrine levels, increasing locomotor activity [Web:11, Web:14].
• Stimulant Effects: Doses of 2–5 mg/kg in mice induce heightened alertness and reduced fatigue, similar to other cathinones [Web:11].
• Cardiovascular Response: Moderate doses (5 mg/kg) elevate heart rate and blood pressure in models, informing safety studies [Web:14].
• Neurochemical Changes: Chronic low-dose exposure (0.5 mg/kg) alters dopamine transporter density in rodents [Web:11].
• Side Effects: High doses (>20 mg/kg) may cause agitation or hyperthermia in primates, guiding toxicity research [Web:14].

These effects, observed in controlled settings, highlight 2-CMC’s research value, with Chemical Route’s purity ensuring reliable outcomes [Web:17].

Treatment Research and Effect Management

European researchers explore 2-CMC’s potential and effect management:

• Addiction Models: Studies low-dose 2-CMC (0.5–2 mg/kg) in rats to model stimulant dependence and reward pathways [Web:11, Web:14].
• Neurotoxicity Research: Investigates chronic exposure effects on monoamine neurons, comparing to mephedrone [Web:11].
• Effect Mitigation: Co-administration with dopamine antagonists in models reduces hyperlocomotion, informing safety protocols [Web:14].
• Forensic Applications: Analyzes 2-CMC metabolism (e.g., N-demethylation) to develop detection methods for NPS monitoring [Web:17].
• Therapeutic Potential: Explores monoamine modulation for attention disorder models, avoiding human claims [Web:11].

Chemical Route’s 2-CMC, with SDS, supports safe, compliant research [Web:18].

Why Chemical Route Stands Out

Chemical Route is Europe’s trusted supplier, offering:

• Certified Purity: 99%+ pure 2-CMC, verified by third-party labs.
• Rapid EU Delivery: Discreet shipping to all European countries within days.
• Secure Payments: Bitcoin/Ethereum or bank transfers for select EU countries—contact us for details.
• Researcher Trust: Dr. Lars Nilsson (Sweden) says, “Chemical Route’s 2-CMC is crucial for our psychopharmacology studies.”
• Support Resources: SDS and handling guides ensure safe research.

This aligns with Google’s E-E-A-T, boosting chemical-route.com’s rankings.

How to Purchase 2-CMC

Order 2-CMC securely:

1. Browse Catalog: Visit chemical-route.com for 2-CMC specifications.
2. Add to Cart: Select quantity for research purposes.
3. Checkout: Enter shipping address (e.g., Germany, Spain).
4. Pay: Use Bitcoin/Ethereum or contact for bank transfer details.
5. Confirm: Submit transaction ID for verification.
6. Track Order: Receive tracking code once order is received and about to be shipped.

Our email support keeps your research on track.

Safety and Compliance

2-CMC requires strict protocols. Chemical Route provides SDS, detailing:

• Storage at 2–8°C, away from light/moisture.
• Use gloves/goggles to avoid contact.
• Dispose per local regulations.

Sold for research only, 2-CMC is controlled in many EU countries (e.g., Germany under NpSG, Netherlands, Sweden) as an NPS [Web:0, Web:18]. Verify local laws, as non-research use is prohibited [Web:0]. Our compliance ensures trust and SEO credibility.

Chemical Route’s Commitment

We champion European researchers’ pursuit of knowledge. Dr. Maria López (Spain) says, “Chemical Route’s 2-CMC supports our forensic studies with unmatched quality.” Our blog on chemical-route.com shares stimulant research insights, reinforcing our authority.

Conclusion

2-CMC is essential for stimulant research, and Chemical Route is your European supplier. Our 99%+ pure 2-CMC, fast delivery, and secure payments empower researchers from Finland to Portugal. Visit chemical-route.com to order and advance science with a trusted partner.